Cat: IPD-X38240

Recombinant Human GAS2 Protein,His

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Analytical Data

  • Gene name

    GAS2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O43903

  • Expression Region

    Gly64~Asp267

  • Molecular Weight

    28kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

GAS2, or Growth Arrest-Specific 2, is a protein that plays a crucial role in various cellular processes, including cell growth, apoptosis, and cytoskeletal organization. Originally identified in studies focused on growth arrest mechanisms, GAS2 has garnered attention due to its involvement in the regulation of actin filaments and its function in cell shape and motility. Research has revealed that GAS2 interacts with several signaling pathways and proteins, suggesting its importance in the response to cellular stress and its potential role in tumor biology. Moreover, mutations or dysregulation of GAS2 have been implicated in several diseases, including cancer, highlighting the necessity for further investigation into its mechanisms of action. The recombinant production of GAS2 allows for detailed studies of its structure-function relationships and its interactions with other cellular components. Understanding the role of GAS2 in cellular dynamics can provide insights into its potential as a therapeutic target and its contribution to disease progression, making it a significant focus of contemporary biomedical research.

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