Analytical Data
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Gene name
PF4
- Application
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Alternative Names
CXCL4; SCYB4; Chemokine C-X-C-Motif Ligand 4; Oncostatin-A; Iroplact
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P02776
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Expression Region
Ala31~Ser101
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Molecular Weight
15kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PF4, or Platelet Factor 4, is a chemokine primarily released by activated platelets, playing a crucial role in hemostasis and inflammation. Its significance extends beyond these functions, as PF4 has been implicated in various pathological conditions, including cardiovascular diseases, cancer, and autoimmune disorders. The recombinant production of PF4 allows for detailed studies on its structure-function relationships and its interactions with other proteins and cells. Research on recombinant PF4 has gained momentum over recent years, driven by its potential as a therapeutic agent in modulating immune responses and its role in promoting wound healing. Understanding the mechanisms underlying PF4's actions can pave the way for innovative therapies targeting thrombotic and inflammatory diseases. Moreover, the development of PF4-based biomaterials has emerged, leveraging its properties to enhance drug delivery systems and tissue engineering applications. Given its diverse physiological role and therapeutic potential, PF4 remains a focal point of investigation in both basic and applied biomedical research. The ability to produce PF4 recombinantly offers researchers the opportunity to elucidate its biological functions and explore its clinical implications more effectively.
