Analytical Data
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基因名
Galectin-4
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简介
Galectin-4 is a lactose-binding protein belonging to the galectin family that exhibits specific affinities for a range of structurally related sugars. This multifunctional protein is noteworthy for its functionality as a monomer, highlighting its individual molecular structure and suggesting that it may exert its biological effects through independent interactions rather than as part of a larger complex. Galectin-4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Galectin-4 protein, expressed by HEK293 , with N-His labeled tag.
- Application
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生物活性
Measured in a cytotoxicity assay using HT-29 cells. The ED50 for this effect is 529.2 ng/mL, corresponding to a specific activity is 1889.645 units/mg. Measured in a cytotoxicity assay using HT-29 cells. The ED50 for this effect is 529.2 ng/mL, corresponding to a specific activity is 1889.645 units/mg.
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别名
LGALS4; L36LBP; Gal-4; Antigen NY-CO-27; Lactose-binding lectin 4
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种属
Mouse
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8K419
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表达区间
M1-I326
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蛋白长度
Full Length
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分子量
37-48 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Galectin-4 is a member of the galectin family of proteins, which are characterized by their affinity for β-galactosides and play crucial roles in various biological processes including cell adhesion, migration, and immune responses. The study of Galectin-4 is particularly significant due to its involvement in several pathological conditions, including cancer, where it can influence tumor growth and metastasis, and inflammatory diseases, which underline its potential as a biomarker and therapeutic target. Recombinant Galectin-4 protein is produced through recombinant DNA technology, which allows for the study of its structure and function in a controlled environment. This research has illuminated the complex interactions of Galectin-4 with other cellular components and has opened avenues for exploring its role in cell signaling and disease progression. Understanding the molecular mechanisms of Galectin-4 can lead to novel therapeutic strategies and enhance our comprehension of its regulatory functions within the immune system and tumor biology. Overall, the investigation of recombinant Galectin-4 protein is crucial for advancing our knowledge of its biological significance and potential clinical applications.
