Analytical Data
-
基因名
BMP3
- Application
-
别名
BMP3A; BMP-3A; Osteogenic
-
种属
Mouse
-
表达系统
HEK293
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8BHE5
-
表达区间
Gly31~Ala355
-
分子量
18kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Bone Morphogenetic Protein 3 (BMP3), a member of the transforming growth factor-beta (TGF-β) superfamily, plays a crucial role in bone development and homeostasis. It was first identified in the context of its ability to induce bone formation, making it a significant focus in regenerative medicine and orthopedics. BMP3 functions primarily as a negative regulator of bone formation; it inhibits osteoblast differentiation and bone graft-induced bone regeneration, contrasting with other BMPs that promote osteogenesis. Research into BMP3 has gained momentum due to its potential implications in treating conditions such as osteoporosis and various bone-related disorders. The recombinant expression of BMP3 protein has proved essential to elucidate its biological functions, signaling pathways, and interactions with other proteins within the BMP family. Recent studies have explored the use of BMP3 in combination therapies for enhanced bone healing, emphasizing its regulatory roles. Understanding the biochemical properties and mechanisms by which BMP3 influences cellular behavior could pave the way for novel therapeutic strategies in bone repair and tissue engineering. Given the complexity of bone biology and the potential for BMP3 to modulate various cellular processes, ongoing research continues to unveil the multifaceted roles of this protein in bone metabolism, positioning it as a significant target for future biomedical applications.
