Analytical Data
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基因名
OV16
- Application
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别名
OV16; OV-16 antigen
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种属
Onchocerca volvulus
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P31729
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表达区间
17-197aa
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分子量
24 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OV16, a recombinant protein derived from the Oncocera virus, has garnered attention in recent years for its potential applications in immunotherapy and cancer treatment. Research has shown that OV16 possesses unique properties that enable it to selectively target and kill cancer cells while sparing normal cells. This selectivity is largely attributed to its ability to exploit specific cellular pathways that are overactive in tumor cells. As cancer remains one of the leading causes of mortality worldwide, the quest for effective treatments is crucial. Traditional therapies, such as chemotherapy and radiation, often come with significant side effects and can lead to resistance, necessitating the development of innovative approaches like OV16. Preliminary studies indicate that OV16 can enhance immune responses against tumors, making it a promising candidate for combination therapies with existing modalities. Moreover, as researchers continue to elucidate the mechanisms underlying OV16's interactions with the immune system and tumor microenvironment, the potential for this recombinant protein to contribute to personalized medicine strategies is becoming increasingly evident. In summary, the ongoing research into OV16 not only highlights the importance of novel therapeutic agents in oncology but also reflects a growing understanding of how targeted treatments can improve patient outcomes and quality of life.












