Recombinant Mouse TMEM106B Protein (HEK293)，hFc

TMEM106B

The TMEM106B protein is a key player in neurons involved in trafficking to late endosomes/lysosomes and potentially affects dendritic morphogenesis and maintenance by regulating lysosomal trafficking. It may act as a molecular brake on retrograde transport by interacting with MAP6. TMEM106B Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TMEM106B protein, expressed by HEK293 , with C-hFc labeled tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Transmembrane protein 106B; Tmem106b

Mouse

HEK293

C-hFc

Greater than 90% as determined by SDS-PAGE.

Q80X71

P119-Q275

Lumenal Domain

65-68 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.