Analytical Data
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Gene name
IL1RAPL1
- Application
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Alternative Names
IL1R8; IL1RAPL; MRX21; MRX34; OPHN4; TIGIRR-2; Mental Retardation,X-Linked 34; Oligophrenin-4; Three immunoglobulin domain-containing IL-1 receptor-related 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q9NZN1
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Expression Region
Ser113~Asp276
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Molecular Weight
25kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1) is a protein that plays a crucial role in the immune system and neuronal function. Its gene is located on the X chromosome, and mutations in IL1RAPL1 have been associated with various neurodevelopmental disorders, including intellectual disabilities and autism spectrum disorders. Given its significance in synaptic development and function, IL1RAPL1 has become a key focus for researchers aiming to understand the molecular mechanisms underlying these conditions. The study of recombinant IL1RAPL1 protein is essential for elucidating its structure-function relationship, which can lead to potential therapeutic approaches. Furthermore, recombinant proteins like IL1RAPL1 can be used in functional assays, allowing scientists to investigate its interactions with other proteins and its effects on cellular signaling pathways. As research progresses, understanding the role of IL1RAPL1 in both normal physiology and pathological conditions may provide insights into novel interventions for neurodevelopmental disorders, highlighting the importance of this protein in both basic and translational research.
