Analytical Data
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基因名
DEFB127
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简介
The DEFB127 protein exhibits significant antibacterial activity, emphasizing its role in the innate immune system's defense against microbial threats. The ability of this protein to defend against bacterial pathogens emphasizes its importance as an effector molecule in host defense mechanisms. DEFB127 Protein, Human (HEK293, Fc) is the recombinant human-derived DEFB127 protein, expressed by HEK293 , with C-hFc labeled tag.
- Application
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别名
Beta-defensin 127; Beta-defensin 27; DEFB-27; C20orf73
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种属
Human
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9H1M4
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表达区间
L21-C63
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蛋白长度
Full Length of Mature Peptide
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DEFB127, a member of the defensin protein family, has garnered significant attention in recent years due to its crucial role in the innate immune response. Found predominantly in human epithelial tissues, particularly in the reproductive tract, DEFB127 exhibits antimicrobial properties against a range of pathogens, including bacteria, viruses, and fungi. This recombinant protein has been the focus of various studies aimed at understanding its functional mechanisms and therapeutic potential. Research has highlighted DEFB127's ability to modulate inflammation and enhance mucosal immunity, which positions it as a promising candidate for applications in treating infections and inflammatory conditions. Furthermore, investigations into its structure-function relationship have revealed insights into how modifications might enhance its activity or stability, paving the way for potential drug development. Given the rising prevalence of antibiotic-resistant infections, DEFB127 offers an alternative approach by harnessing natural defense mechanisms. Overall, the exploration of DEFB127 as a recombinant protein not only enriches our understanding of host defense strategies but also opens avenues for therapeutic interventions that could complement existing antimicrobial treatments.
