Analytical Data
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基因名
CCDC47
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简介
The CCDC47 protein is an important component of the multichannel translocon (MPT) complex and cooperates with SEC61 to mediate the insertion of multichannel membrane proteins. As part of the PAT subcomplex within MPT, CCDC47 helps sequester polar regions within the transmembrane domain, ensuring correct membrane protein assembly. CCDC47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CCDC47 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
PAT complex subunit CCDC47; Calumin; Adipocyte-specific protein 4; Asp4
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种属
Mouse
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9D024
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表达区间
K21-S135
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蛋白长度
Cytoplasmic Domain
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分子量
20-23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC47 (Coiled-Coil Domain Containing 47) is a protein that has garnered attention in recent years due to its potential roles in various biological processes, particularly in the context of cellular function and regulation. Initially identified as a gene associated with cellular stress responses, CCDC47 has been implicated in important cellular pathways such as cell proliferation, differentiation, and apoptosis. Its coiled-coil domain structure suggests potential interactions with other proteins, making it a candidate for involvement in complex protein networks. Research has indicated that CCDC47 may play a significant role in diseases, including cancer, where altered expression levels have been reported. The study of recombinant CCDC47 protein aims to elucidate its functional properties, mechanisms of action, and interaction partners, which could provide insights into its biological significance. By generating recombinant CCDC47, researchers hope to investigate its structural characteristics and functional roles in vitro, paving the way for potential therapeutic applications and a deeper understanding of its contribution to disease pathology. This research could ultimately lead to novel strategies for targeting CCDC47 in disease contexts, particularly in malignancies where its expression is dysregulated. As interest in CCDC47 continues to grow, further investigations into its biological implications and the molecular mechanisms underlying its functions remain crucial for advancing our knowledge in cellular biology and disease mechanisms.
