Analytical Data
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Gene name
HIST2H2BE
- Application
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Alternative Names
H2BFQ; H2B/q; H2B.1; H2B Histone Family Member Q
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16778
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Expression Region
Pro2~Lys126
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Molecular Weight
18kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HIST3H2A is a variant of the histone H2A family, playing a crucial role in the packaging and regulation of DNA within the nucleus. Histones are fundamental components of chromatin, which influences gene expression, DNA replication, and repair processes. The study of HIST3H2A is particularly significant in the context of epigenetics, where modifications of histones can lead to heritable changes in gene activity not caused by alterations in the DNA sequence itself. Research on HIST3H2A has gained momentum due to its implications in various biological processes, including development, cell differentiation, and response to environmental stimuli. Moreover, aberrations in histone modifications and expression patterns are associated with numerous diseases, including cancer, making HIST3H2A a potential biomarker and therapeutic target. Understanding the structure and function of HIST3H2A, as well as its interaction with other histones and regulatory proteins, can provide valuable insights into the intricate regulatory networks governing genomic stability and cellular function. The recombinant production of HIST3H2A allows researchers to explore its biochemical properties, study post-translational modifications, and assess its role in chromatin dynamics, thereby advancing our knowledge of epigenetic regulation and potential mechanisms underlying disease development. Through these investigations, scientists aim to develop novel strategies for manipulating gene expression and advancing therapeutic approaches in regenerative medicine and oncology.
