Analytical Data
-
基因名
Carnosine Dipeptidase 1/CNDP1
-
简介
Carnosine Dipeptidase 1 Protein, Human (HEK293, His) is a human carnosine dipeptidase 1 protein with a his-flag, expressed in HEK293 cells. Carnosine Dipeptidase 1 is a member of the M20 metalloprotease family, encoded by the CNDP1 gene[1].
- Application
-
别名
rHuCarnosine Dipeptidase 1, His; Beta-Ala-His Dipeptidase; CNDP Dipeptidase 1; Carnosine Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; Serum Carnosinase; CNDP1; CN1; CPGL2
-
种属
Human
-
表达系统
HEK293
-
标签
C-6*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96KN2
-
表达区间
S27-L506
-
氨基酸序列
SPSPPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLGARVASVDMGPQQLPDGQSLPIPPIILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDSSGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAFFLEMAQLHHHHHHH
-
蛋白长度
Full Length of Mature Protein
-
分子量
60-90 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Carnosine Dipeptidase 1 (CNDP1) is an important enzyme involved in the metabolism of dipeptides, particularly carnosine, which is a natural antioxidant and has various physiological roles, including muscle endurance, neuroprotection, and potential anti-aging effects. The CNDP1 enzyme catalyzes the hydrolysis of carnosine into its constituent amino acids, thereby regulating the levels of this dipeptide in tissues. Recent studies have highlighted the significance of CNDP1 in various pathological conditions, such as diabetes and neurodegenerative diseases, suggesting that modulation of its activity could have therapeutic implications. The recombinant production of CNDP1 offers a valuable tool for understanding its biochemical properties and functional mechanisms. Researchers are keen on characterizing this enzyme to elucidate its role in physiological and pathological processes, as well as to explore potential applications in biomedical research and therapeutic interventions. By generating a stable source of CNDP1, scientists can investigate its substrate specificity, kinetic parameters, and regulatory mechanisms, which are crucial for developing novel strategies to manipulate its activity in disease contexts. Furthermore, CNDP1's involvement in modulating the effects of oxidative stress and inflammation positions it as a promising target for drug development aimed at enhancing healthspan and treating age-related disorders.
