Analytical Data
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基因名
AARSD1
- Application
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别名
Alanyl-tRNA editing protein Aarsd1; Alanyl-tRNA synthetase domain-containing protein 1; AARSD1
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9BTE6-2
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表达区间
T176-E525
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氨基酸序列
TINDISVLRVTRRGEQADHFTQTPLDPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEVEQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNRTNLIFLSGNRVLKWMERSHGTEKALTALLKCGAEDHVEAVKKLQNSTKILQKNNLNLLRDLAVHIAHSLRNSPDWGGVVILHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGGGLFLLAGPPASVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRMEAQALLQDYISTQSAKE
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蛋白长度
Partial
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分子量
40 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AARSD1, or Arylsulfatase D1, is a recently identified member of the arylsulfatase family, which plays a crucial role in the hydrolysis of sulfate esters in various biological processes. Research on AARSD1 has gained momentum due to its potential implications in human health and disease, particularly in the context of metabolic disorders and neurological conditions. The enzyme's activity is linked to the degradation of sulfated metabolites, which are vital for cellular signaling, hormone regulation, and the maintenance of extracellular matrix components. Studies have shown that mutations or dysregulation of AARSD1 can contribute to pathological states, emphasizing the need for detailed investigation into its structure and function. Recombinant expression of AARSD1 allows for the production of the protein in a controlled laboratory environment, facilitating the exploration of its enzymatic properties and substrate specificity. Understanding the mechanistic details of AARSD1 can aid in uncovering its biological significance, potential role as a biomarker, and suitability as a therapeutic target. The ongoing research aims to elucidate the function of this enzyme in various physiological and pathological contexts, providing insights that could lead to novel interventions for diseases associated with sulfate metabolism dysfunction.
