Analytical Data
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基因名
Alpha 1-Microglobulin
- Application
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别名
AMBP; UTI; HCP; EDC1; HI30; IATIL; ITILC; ITI; ITIL; Alpha 1 Microglobulin/Bikunin Precursor; Growth-inhibiting protein 19; Uristatin; Uronic-Acid-Rich Protein; Trypstatin
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种属
Human
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P02760
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表达区间
Gly20~Arg202
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分子量
35kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Alpha 1-Microglobulin (A1M) is a small plasma protein that plays a crucial role in various physiological processes, including immune response, as well as protecting tissues from oxidative stress and inflammation. Its potential therapeutic applications have garnered significant interest in recent years, particularly due to its protective properties against kidney damage and other organ injuries. Research has shown that A1M can act as a scavenger for free radicals, thereby mitigating cellular damage in conditions such as sepsis, acute kidney injury, and chronic inflammatory diseases. The recombinant production of A1M has enabled researchers to study its structure-function relationships more effectively and to explore its potential as a biotherapeutic agent. Advances in recombinant DNA technology have facilitated the large-scale synthesis of A1M, providing a consistent and homogeneous product for both experimental and clinical applications. Moreover, ongoing studies are investigating the immunomodulatory effects of A1M, along with its ability to improve outcomes in transplantation and enhance tissue regeneration. Overall, the exploration of recombinant A1M represents a promising avenue for developing new therapeutic strategies to combat various diseases associated with oxidative stress and inflammation.












