Analytical Data
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基因名
TMX2
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简介
The TMX2 protein is an endoplasmic reticulum- and mitochondria-associated regulator that controls cellular redox status and affects post-translational modifications, protein folding, and mitochondrial activity. TMX2 Protein, Human (His) is the recombinant human-derived TMX2 protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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别名
Thioredoxin-related transmembrane protein 2; Cell proliferation-inducing gene 26 protein; Thioredoxin domain-containing protein 14; TMX2
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y320-1
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表达区间
M125-K296
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蛋白长度
Partial
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分子量
21.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMX2 (Transmembrane and Tetratricopeptide Repeats 2) is a protein that plays a crucial role in various cellular processes, particularly in the regulation of endoplasmic reticulum (ER) stress and protein homeostasis. The protein is characterized by its transmembrane domains and tetratricopeptide repeat motifs, which are known for mediating protein-protein interactions. Research has shown that TMX2 is involved in the modulation of the unfolded protein response (UPR), a cellular mechanism that helps maintain ER function under stress conditions. Dysregulation of TMX2 has been implicated in several diseases, including cancer and neurodegenerative disorders. This has spurred interest in the study of TMX2 as a potential therapeutic target, with a focus on understanding its structure, function, and interactions within cellular signaling pathways. Recombining TMX2 protein for experimental studies allows researchers to investigate its role in disease mechanisms and to explore its potential as a biomarker or therapeutic target, thereby broadening our understanding of cellular stress responses and pathological conditions.
