Analytical Data
-
基因名
CSNK2A1
-
简介
The CSNK2A2 protein is a constitutively active kinase that phosphorylates substrates and controls the cell cycle, apoptosis, and transcription. CSNK2A1 Protein, Human (His) is the recombinant human-derived CSNK2A1, expressed by E. coli , with His labeled tag.
- Application
-
别名
CSNK2A1; casein kinase 2 alpha 1; CKII; Cka1; Cka2; CK2A1; OCNDS
-
种属
Human
-
表达系统
E. coli
-
标签
His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P68400-1
-
表达区间
M1-Q391
-
蛋白长度
Full Length of Isoform-1
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CSNK2A1, or Casein Kinase II Alpha 1, is a serine/threonine kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Its deregulation has been associated with multiple cancers and other diseases, making it a significant target for therapeutic intervention. Research into CSNK2A1 has revealed its involvement in the phosphorylation of a wide range of substrates, influencing critical signaling pathways that control cell cycle and survival. The development of recombinant CSNK2A1 proteins allows for in-depth studies on its enzymatic activity, substrate specificity, and structural characteristics. By producing and characterizing these recombinant proteins, researchers aim to elucidate the functional mechanisms of CSNK2A1 in normal physiology and disease states. Understanding its role at a molecular level could provide insights for developing novel treatments and targeted therapies, particularly in malignancies where CSNK2A1 is overexpressed or hyperactive. Thus, the study of CSNK2A1 recombinant proteins is instrumental in advancing our knowledge of kinase function and its implications in cellular signaling networks.
