Analytical Data
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Gene name
XG/Xg blood group
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简介
XG/Xg blood group Protein is a type I transmembrane glycoprotein belonging to the CD99 family. It is a erythrocyte membrane protein that is used as the basis of the Xg blood group system. XG/Xg blood group Protein, Human (HEK293, His) is the recombinant human-derived XG/Xg blood group protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Glycoprotein Xg; Protein PBDX; Xg; XGPY
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
P55808-2
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Expression Region
Q22-K143
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Protein Length
Partial
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Molecular Weight
21 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The XG blood group system is a significant yet often overlooked component of human blood group antigens, which are critical in transfusion medicine and organ transplantation. Identified primarily through the unique Xg antigen, this system exhibits particular complexity due to its genetic basis linked to the X chromosome, affecting primarily females and presenting unique challenges in serological testing. Research into XG/Xg blood group recombinant proteins has gained momentum due to their potential implications in understanding immune responses, disease susceptibility, and compatibility in blood transfusions. The recombinant proteins serve as valuable tools in elucidating the biological functions of these antigens, enabling investigators to explore their roles in red blood cell morphology and immune interactions. Furthermore, these studies could lead to the development of new diagnostic assays and enhanced transfusion strategies, particularly for populations with rare blood types. The ongoing research into XG/Xg antigens not only contributes to the field of hematology but also intersects with genetics and immunology, paving the way for improved outcomes in blood-related therapies and a deeper understanding of human genetic diversity.
