Analytical Data
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Gene name
PPIC
- Application
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Alternative Names
PPI-C; CYPC; Cyclophilin C; Peptidyl Prolyl Cis/Trans Isomerase C; Rotamase C
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P45877
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Expression Region
Pro5~Val201
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Molecular Weight
51kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPIC, or Protein Prolyl Isomerase C, is a crucial enzyme that plays a significant role in the folding and function of various proteins within the cell. Understanding the mechanisms behind PPIC and its behavior in protein folding has garnered interest due to its implications in various physiological and pathological processes. Research into PPIC is essential, particularly in the context of diseases where protein misfolding is involved, such as neurodegenerative disorders and certain types of cancer. By studying the reconstitution of PPIC, scientists aim to uncover its specific functions, interactions with other molecular chaperones, and its role in the cellular stress response. Reconstituted PPIC can serve as a valuable tool for investigating the enzyme's catalytic activity and substrate specificity, which could lead to novel therapeutic strategies. Furthermore, understanding PPIC can enhance the efficacy of protein-based pharmaceuticals by optimizing protein folding processes. As researchers delve deeper into the intricacies of PPIC and its applications in biotechnology and medicine, the potential to harness its capabilities for improving protein stability and functionality becomes increasingly promising.
