Analytical Data
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基因名
CAMK1 alpha
- Application
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别名
CAMKI; CaM kinase I alpha
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14012
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表达区间
Met1~Leu370
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分子量
45kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CAMK1 alpha, or calcium/calmodulin-dependent protein kinase 1 alpha, is a serine/threonine kinase that plays a crucial role in various cellular processes, including muscle contraction, gene expression, and neuronal signaling. As a member of the calcium/calmodulin-dependent protein kinase family, CAMK1 alpha is activated in response to increases in intracellular calcium levels, which links calcium signaling to numerous biological effects. Research has shown that CAMK1 alpha is involved in critical physiological processes such as synaptic plasticity, which is vital for learning and memory, as well as in the regulation of circadian rhythms. Dysregulation of CAMK1 alpha has been implicated in several pathologies, including neurodegenerative diseases and cancer. Therefore, the study of recombinant CAMK1 alpha protein is of significant interest to elucidate its function, regulatory mechanisms, and potential therapeutic targets. By producing and characterizing recombinant CAMK1 alpha, researchers aim to gain insights into its biochemical properties and interactions with other proteins in signaling pathways. This knowledge may contribute to the understanding of its role in health and disease, potentially leading to novel interventions or drug developments. Overall, the exploration of CAMK1 alpha at the molecular level represents an important frontier in the research of cellular signaling and its implications for human health.












