Cat: IPD-X29590

Recombinant Mouse Prok2 Protein,B2M & His

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Analytical Data

  • Gene name

    Prok2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Prokineticin-2; Prok2; Protein Bv8 homolog; Bv8

  • Species

    Mouse

  • Source

    E. coli

  • Tag

    N-B2M;N-6*His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9QXU7

  • Expression Region

    A27-K128

  • Protein Length

    Full Length of Mature Protein

  • Molecular Weight

    25-30 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Prokineticin 2 (Prok2) is a secreted protein that plays a crucial role in various physiological processes, including the regulation of circadian rhythms, reproductive functions, and neuronal signaling. It is part of the prokineticin family, which interacts with its receptors, PKR1 and PKR2, to mediate its biological effects. Research has revealed that Prok2 is involved in critical functions such as promoting gastrointestinal motility and influencing mood regulation through its action in the central nervous system. The study of recombinant Prok2 has gained prominence due to its potential therapeutic applications in conditions like gastrointestinal disorders, mood disorders, and sleep disturbances. By producing recombinant Prok2 in various expression systems, researchers can investigate its structure-function relationships and pharmacological properties in greater detail. This research aims to elucidate the molecular mechanisms underlying Prok2's actions and explore its potential as a target for drug development. The increased understanding of Prok2's role in physiology and its mechanisms of action could lead to new insights into treating diseases associated with its dysregulation, marking significant advancements in both fundamental biology and clinical applications.

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