Analytical Data
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Gene name
CCN5
- Application
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Alternative Names
CCN family member 5 Connective tissue growth factor-like protein Short name: CTGF-L
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Species
Mouse
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Source
Yeast
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Z0G4
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Expression Region
24-251aa
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Molecular Weight
26.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCN5, also known as connective tissue growth factor (CTGF) family member 5, is a member of the CCN (Cyr61, CTGF, NOV) family of matricellular proteins, which are implicated in various biological processes, including cell adhesion, migration, proliferation, and extracellular matrix regulation. Research into CCN5 has gained momentum due to its potential role in cellular signaling pathways that influence tissue repair and fibrosis, particularly in cardiovascular disease, cancer, and metabolic disorders. Studies have indicated that CCN5 may play a protective role against cardiac hypertrophy and fibrosis, suggesting its involvement in cardiac health. Furthermore, aberrant expression of CCN5 has been linked to tumor progression and metastasis, making it a critical target for cancer research. The recombinant production of CCN5 protein allows for detailed functional studies and characterization of its molecular mechanisms. Understanding the structure-function relationship of CCN5 can unveil its therapeutic potential, thereby highlighting the importance of developing reliable methods for its recombinant expression and purification. This knowledge may open doors for new interventions in diseases where CCN5 is dysregulated, further emphasizing the need for comprehensive research on this protein in various biological contexts.
