Analytical Data
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基因名
SLK
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简介
The SLK protein is a bifunctional mediator that affects apoptosis and actin stress fiber lysis, suggesting a role in programmed cell death and regulation of cytoskeletal dynamics. The specific molecular mechanisms coordinating these processes need to be further elucidated to facilitate research on the functional significance of SLK. SLK Protein, Human (sf9, GST) is the recombinant human-derived SLK protein, expressed by sf9 insect cells , with N-GST labeled tag.
- Application
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别名
SLK; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2
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种属
Human
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表达系统
Baculovirus
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标签
N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H2G2
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表达区间
M1-T1152
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The research on SLK (Ste20-like kinase) recombinant protein has gained significant attention due to its crucial role in various cellular processes, particularly in the regulation of cell motility, proliferation, and apoptosis. SLK is a serine/threonine kinase that belongs to the Ste20 family, characterized by its involvement in signaling pathways that govern cytoskeletal dynamics and cell behavior. Dysregulation of SLK activity has been implicated in several pathological conditions, including cancer metastasis and other diseases characterized by abnormal cell growth and movement. By studying SLK in its recombinant form, researchers aim to elucidate its functional mechanisms, interaction partners, and downstream effects. This includes exploring its potential as a therapeutic target, as modulating SLK activity could lead to novel strategies for controlling cancer progression and improving patient outcomes. Additionally, the recombinant expression of SLK allows for the production of purified protein for structural and functional assays, thereby accelerating the understanding of its role in cellular signaling networks. Hence, the research on SLK recombinant protein not only enhances our knowledge of fundamental biological processes but also opens avenues for innovative therapeutic interventions against diseases associated with its dysregulation.
