Analytical Data
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Gene name
GAS7
- Application
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60861
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Expression Region
Met1~Asp456
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Molecular Weight
56kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The GAS7 (Growth Arrest-Specific 7) protein, initially identified in a study focused on genes expressed during growth arrest, has garnered significant attention due to its pivotal role in neuronal differentiation and brain development. Research indicates that GAS7 is involved in various cellular processes, including cytoskeletal dynamics, cellular signaling, and apoptosis. Its expression is particularly pronounced in the nervous system, suggesting that it may play a critical role in neurogenesis and the maintenance of neuronal structures. Studies have shown that GAS7 interacts with several key proteins and pathways that regulate actin cytoskeleton remodeling, which is crucial for neuronal shape and function. Additionally, alterations in GAS7 expression have been implicated in neurodegenerative diseases and conditions such as schizophrenia, underscoring its potential as a therapeutic target. The recombinant expression and functional characterization of GAS7 are essential for elucidating its biological roles and mechanisms. This research aims to produce high-quality GAS7 recombinant protein to facilitate studies on its structure, function, and interactions, thereby advancing our understanding of its contributions to neurobiology and related disorders. By uncovering the precise functions of GAS7, we hope to provide insights that could lead to innovative strategies for treating neurodevelopmental and neurodegenerative diseases, paving the way for novel therapeutic interventions.
