Analytical Data
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Gene name
VAT1L
- Application
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Alternative Names
VAT1L; Synaptic vesicle membrane protein VAT-1 homolog-like;
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Species
Human
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Source
E. coli
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Tag
C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HCJ6
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Expression Region
M1-Q419
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AA Sequence
MAKEGVEKAEETEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ
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Protein Length
Full Length
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Molecular Weight
52.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
VAT1L is a neuronal protein that plays a crucial role in synaptic transmission and has been implicated in various neurological disorders. Its involvement in the regulation of neurotransmitter release and synaptic plasticity has garnered interest in the scientific community, particularly in understanding its potential role in conditions such as schizophrenia, autism, and bipolar disorder. Recent studies have suggested that VAT1L may affect the transport and release of synaptic vesicles, which are essential for communication between neurons. Given the increasing prevalence of neuropsychiatric conditions and the complexity of synaptic mechanisms, research on VAT1L is particularly significant. Investigations into its structure, function, and the molecular pathways it interacts with may reveal insights into the pathophysiology of these disorders and aid in the development of targeted therapies. Furthermore, the exploration of VAT1L as a biomarker for neurological diseases is an area of emerging interest. Understanding the precise roles and mechanisms of VAT1L could provide a foundation for novel interventions in the management of mental health disorders, making this an important focus for ongoing research in neuroscience.











