Analytical Data
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Gene name
HSP90AA1
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简介
The HSP90AA1 protein is an important molecular chaperone that coordinates the maturation and regulation of specific target proteins critical for cell cycle control and signal transduction. Its ATPase activity drives a functional cycle that induces conformational changes in client proteins for activation. HSP90AA1 Protein, Human (His, Avi) is the recombinant human-derived HSP90AA1, expressed by E. coli , with C-Avi, C-6*His labeled tag. ,
- Application
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Species
Human
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Source
E. coli
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Tag
C-Avi;C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P07900-1
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Expression Region
M1-D732
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Protein Length
Full Length of Isoform-1
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NPR1 (Nonexpressor of Pathogenesis-Related Genes 1) is a pivotal protein in plant immunity, particularly in Arabidopsis thaliana, that acts as a master regulator in the salicylic acid (SA) signaling pathway. Identified as a key player in plant defense mechanisms, NPR1 modulates the expression of pathogenesis-related (PR) genes in response to pathogen attacks. Its activity is crucial for the establishment of systemic acquired resistance (SAR), a form of induced resistance that protects plants from subsequent infections. Research on NPR1 has gained momentum due to its potential applications in enhancing crop resistance to diseases, addressing the growing challenges of sustainable agriculture and food security. Understanding the molecular mechanisms governing NPR1's function can lead to innovative strategies in crop improvement, leveraging genetic engineering and biotechnological approaches to enhance resistance in economically significant crops. Recent studies have unraveled NPR1's interaction with various signaling pathways and its role in coordinating stress responses, making it a target for research aimed at developing resilient plant varieties. Thus, NPR1 serves as a focal point for deciphering the complex interplay between plant defense signaling and environmental stress responses, paving the way for advancements in agricultural practices through improved disease management.
