Analytical Data
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Gene name
DLK2
- Application
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Alternative Names
Epidermal growth factor-like protein 9 ;EGF-like protein 9
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UY11
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Expression Region
27-306aa
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Molecular Weight
56.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DLK2 (Dual Leucine Zipper Kinase 2) is a member of the MAPK (Mitogen-Activated Protein Kinase) kinase family, which plays a crucial role in various cellular processes, including differentiation, apoptosis, and response to stress signals. Research has increasingly focused on DLK2 due to its involvement in neurodevelopment and its potential implications in neurodegenerative diseases and cancer. The protein is known to be activated in response to stress stimuli and can regulate signal transduction pathways that control cell fate decisions. Given its dual role as both a kinase and a transcription factor, understanding the regulatory mechanisms of DLK2 is essential for elucidating its function in cell signaling. Recombinant DLK2 proteins are generated for biochemical and structural studies, which facilitate the exploration of its interactions with other cellular proteins and the downstream signaling pathways. Moreover, these studies aim to uncover the potential of DLK2 as a therapeutic target in diseases marked by dysregulated cell signaling. Researchers are particularly interested in the development of small-molecule inhibitors that could modulate DLK2 activity, opening new avenues for targeted therapies in disorders where DLK2 is implicated. Overall, the investigation of DLK2 recombinant proteins not only enhances our understanding of its biological significance but also contributes to the broader field of cellular signaling and therapeutic development.
