Analytical Data
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Gene name
SLC35F2
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简介
SLC35F2 Protein, a putative solute transporter, potentially participates in the cellular transport of various solutes. Despite the lack of clarity on specific substrates and transport mechanisms, its designation implies a role in regulating intracellular solute concentrations. Precise details of its transport function and impact on cellular physiology require further research. SLC35F2 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC35F2 protein, expressed by sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.
- Application
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Alternative Names
SLC35F2; Solute carrier family 35 member F2
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Species
Human
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Source
Baculovirus
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Tag
N-StrepⅡ;N-8*His;C-Flag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IXU6
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Expression Region
E2-L374
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC19A2, a key gene encoding a member of the solute carrier family, plays a crucial role in the transport of thiamine (vitamin B1) and is vital for cellular energy metabolism. Mutations in the SLC19A2 gene are implicated in selective deficiency of thiamine, leading to conditions such as Beri-Beri and Wernicke-Korsakoff syndrome. As thiamine is essential for proper functioning of the nervous system and metabolism, understanding the functioning and regulation of the SLC19A2 protein is critical for addressing these health issues. Research focused on the recombinant expression of SLC19A2 has garnered attention as it enables the production of functional protein for in vitro studies. This, in turn, facilitates the elucidation of the protein's transport mechanisms, structural characteristics, and interaction with thiamine. Recombinant SLC19A2 can be utilized to investigate the effects of various mutations on protein function, thus providing insights into the pathophysiology of related disorders. Furthermore, studying the recombinant protein offers a foundation for potential therapeutic strategies aimed at enhancing thiamine transport in affected individuals. By understanding the molecular basis of SLC19A2-related conditions, researchers aim to contribute to improved diagnostic, preventive, and treatment options for diseases rooted in thiamine deficiency.
