Analytical Data
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基因名
MAP3K1
- Application
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别名
MAPK/ERK kinase kinase 1 ;MEK kinase 1 ;MEKK 1
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种属
Mouse
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P53349
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表达区间
1216-1493aa
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分子量
34.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MAP3K1 (Mitogen-activated protein kinase kinase kinase 1) is a crucial component in the MAPK signaling pathways, which play significant roles in regulating various cellular processes such as proliferation, differentiation, and apoptosis. Abnormalities in MAP3K1 have been implicated in several cancers and developmental disorders, making it an important target for therapeutic intervention. Research on MAP3K1 recombinant protein has gained attention due to its potential implications in understanding the molecular mechanisms underlying these diseases. By studying the structure and function of MAP3K1, scientists aim to elucidate its role in signal transduction and identify how its dysregulation contributes to pathological conditions. Recombinant MAP3K1 protein can be utilized for various experimental approaches, including enzyme assays, interaction studies, and inhibitor screenings, thereby providing valuable insights into its therapeutic potential. Additionally, understanding the post-translational modifications and regulatory mechanisms of MAP3K1 could shed light on its functional diversity in different biological contexts. Consequently, the investigation of MAP3K1 recombinant protein is a promising area of research that may lead to novel strategies for disease treatment and prevention.
