Analytical Data
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Gene name
MAP3K1
- Application
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Alternative Names
MAP3-K1; MAPKKK1; MEKK; MEKK1
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q13233
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Expression Region
Ile1307~Arg1509
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Molecular Weight
26kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAP3K1 (Mitogen-activated protein kinase kinase kinase 1) is a crucial component in the MAPK signaling pathways, which play significant roles in regulating various cellular processes such as proliferation, differentiation, and apoptosis. Abnormalities in MAP3K1 have been implicated in several cancers and developmental disorders, making it an important target for therapeutic intervention. Research on MAP3K1 recombinant protein has gained attention due to its potential implications in understanding the molecular mechanisms underlying these diseases. By studying the structure and function of MAP3K1, scientists aim to elucidate its role in signal transduction and identify how its dysregulation contributes to pathological conditions. Recombinant MAP3K1 protein can be utilized for various experimental approaches, including enzyme assays, interaction studies, and inhibitor screenings, thereby providing valuable insights into its therapeutic potential. Additionally, understanding the post-translational modifications and regulatory mechanisms of MAP3K1 could shed light on its functional diversity in different biological contexts. Consequently, the investigation of MAP3K1 recombinant protein is a promising area of research that may lead to novel strategies for disease treatment and prevention.
