Analytical Data
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基因名
CECR2
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简介
The CECR2 protein is a regulatory subunit in the CERF-1 and CERF-5 ISWI chromatin remodeling complexes that assembles ordered nucleosome arrays to help DNA enter replication, transcription, and repair. Despite lacking mononucleosome sliding ability, these complexes make crucial contributions to various developmental processes. CECR2 Protein, Human (His) is the recombinant human-derived CECR2 protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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别名
CECR2; Cat eye syndrome critical region protein 2
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BXF3
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表达区间
R425-H538
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CECR2 (Cat Eye Syndrome Chromosome Region Candidate 2) is a protein that plays a significant role in developmental processes and cellular differentiation. It has been implicated in various biological functions, including chromatin remodeling and gene regulation, primarily in embryonic development. Mutations or dysregulation of CECR2 are associated with cat eye syndrome, a genetic condition characterized by a range of developmental abnormalities, particularly affecting the eyes and urinary tract. Recent studies have highlighted the importance of CECR2 in neuronal differentiation and its potential involvement in neurodevelopmental disorders. Research into CECR2 recombinant protein focuses on understanding its structural and functional properties, which could reveal insights into its role in cellular mechanisms and disease pathways. The production and characterization of CECR2 recombinant protein allow for detailed functional assays, enabling researchers to investigate its interactions with other cellular components and its effects on gene expression. This research has important implications for understanding the underlying mechanisms of diseases associated with CECR2 mutations and could lead to the development of novel therapeutic strategies targeting related pathways.
