Analytical Data
-
Gene name
SAA4
- Application
-
Alternative Names
C-SAA; CSAA; SA-A4; Constitutively expressed serum amyloid A protein
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P35542
-
Expression Region
Glu19~Tyr130
-
Molecular Weight
33kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SAA4, or serum amyloid A4, is a protein that plays a significant role in the body's acute inflammatory response and has been implicated in various pathophysiological conditions, including cardiovascular diseases and amyloidosis. The SAA4 gene is part of the serum amyloid A family, which is primarily produced by the liver in response to inflammatory stimuli such as infection or tissue injury. Research on SAA4 has gained attention due to its potential as a biomarker for inflammatory diseases and its involvement in the development of atherosclerosis. As a key player in the inflammation process, SAA4 orchestrates the recruitment of immune cells and contributes to the modulation of lipid metabolism. Recent studies have focused on the structural and functional characterization of SAA4, particularly its role in the formation of amyloid deposits that can lead to organ dysfunction. The recombinant production of SAA4 protein allows researchers to delve deeper into its functional properties and interactions, enabling the exploration of therapeutic interventions and diagnostic tools. Understanding the molecular mechanisms by which SAA4 participates in inflammation and amyloidogenesis is critical for developing strategies aimed at mitigating its pathological effects, thereby advancing the field of inflammatory disease research. Continued investigation into SAA4 will not only enhance our comprehension of its biological significance but also support the identification of novel therapeutic targets for conditions linked to chronic inflammation and amyloid-related disorders.
