Recombinant Dog Creatine kinase M-type/CKM Protein，His

Creatine kinase M-type (CKM) is an important enzyme involved in cellular energy metabolism, primarily found in skeletal and cardiac muscles. It plays a critical role in the ATP-PCr energy system, facilitating the transfer of high-energy phosphate groups from phosphocreatine to adenosine diphosphate (ADP) to generate adenosine triphosphate (ATP), especially during short bursts of high-intensity exercise. Research into CKM has gained momentum due to its potential implications in various physiological and pathological conditions, including muscle disorders, heart diseases, and metabolic syndromes. The ability to produce recombinant CKM protein has facilitated detailed studies on its structure, function, and regulation, allowing scientists to explore its enzymatic mechanisms and interaction with other cellular components. Furthermore, understanding CKM's role can lead to novel therapeutic strategies for energy metabolism-related diseases. The advent of recombinant DNA technology enables the production of high-purity CKM, which is essential for biochemical assays, structural studies, and drug development. This research is vital not only for basic science but also for translational applications in medicine and sports science, emphasizing the importance of CKM in maintaining energy homeostasis in muscle tissues.