Analytical Data
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Gene name
SULT2B1
- Application
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Alternative Names
Alcohol sulfotransferase Hydroxysteroid sulfotransferase 2
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O00204
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Expression Region
1-365aa
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Molecular Weight
68.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SULT2B1, a member of the sulfotransferase enzyme family, plays a crucial role in the sulfonation of various endogenous and exogenous compounds, including steroid hormones and drugs. This enzyme is responsible for the sulfate conjugation process, which enhances the solubility and excretion of these compounds, thereby influencing their biological activity and pharmacokinetics. Research into SULT2B1 has gained significance due to its involvement in steroid metabolism and potential association with various diseases, such as hormone-related cancers and metabolic disorders. Genetic variations and expression levels of SULT2B1 have been linked to individual differences in drug responses and susceptibility to diseases, making it a potential biomarker for personalized medicine. Additionally, the production of recombinant SULT2B1 proteins is essential for understanding the enzyme's structure-function relationships, enzymatic mechanisms, and interaction with substrates, which can further aid in drug development and the design of targeted therapies. As such, studies focusing on the recombinant production and functional characterization of SULT2B1 are pivotal in elucidating its physiological roles and clinical implications, providing insights that could lead to more effective therapeutic strategies targeting metabolic and endocrine disorders.
