Analytical Data
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基因名
PARP7
- Application
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别名
(ADP-ribosyltransferase diphtheria toxin-like 14)(ARTD14)(Poly [ADP-ribose] polymerase 7)(PARP-7)(TCDD-inducible poly [ADP-ribose] polymerase)
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种属
Human
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表达系统
Baculovirus
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标签
C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z3E1
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表达区间
1-657aa
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分子量
79.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PARP7, also known as poly(ADP-ribose) polymerase 7, is a member of the PARP family of enzymes, which are primarily involved in cellular processes such as DNA repair, gene regulation, and cellular stress response. The study of PARP7 has gained significant attention due to its unique roles in various biological contexts, particularly in cancer biology. Unlike other PARP proteins, PARP7 plays a critical role in modulating the activity of key signaling pathways and is implicated in the regulation of inflammation and immune responses. Recent research has identified PARP7 as a potential therapeutic target in several cancer types, as it appears to influence tumor growth and survival. The development of recombinant PARP7 proteins has facilitated the investigation of its enzymatic functions, substrate interactions, and potential as a drug target. By understanding the molecular mechanisms underlying PARP7 activity, researchers aim to uncover its contributions to disease mechanisms and to explore its utility in novel treatment strategies, particularly in cancers characterized by altered PARP signaling. This growing body of research highlights the significance of PARP7 not only in cancer but also in broader contexts of cell biology, paving the way for innovative therapeutic interventions that could enhance patient outcomes.
