Analytical Data
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Gene name
PARP7
- Application
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Alternative Names
PARP7
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Species
Human
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Source
E. coli
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Tag
N-His;N-Avi
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z3E1
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Expression Region
M456-I657
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Protein Length
Partial
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Molecular Weight
28.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PARP7, also known as poly(ADP-ribose) polymerase 7, is a member of the PARP family of enzymes, which are primarily involved in cellular processes such as DNA repair, gene regulation, and cellular stress response. The study of PARP7 has gained significant attention due to its unique roles in various biological contexts, particularly in cancer biology. Unlike other PARP proteins, PARP7 plays a critical role in modulating the activity of key signaling pathways and is implicated in the regulation of inflammation and immune responses. Recent research has identified PARP7 as a potential therapeutic target in several cancer types, as it appears to influence tumor growth and survival. The development of recombinant PARP7 proteins has facilitated the investigation of its enzymatic functions, substrate interactions, and potential as a drug target. By understanding the molecular mechanisms underlying PARP7 activity, researchers aim to uncover its contributions to disease mechanisms and to explore its utility in novel treatment strategies, particularly in cancers characterized by altered PARP signaling. This growing body of research highlights the significance of PARP7 not only in cancer but also in broader contexts of cell biology, paving the way for innovative therapeutic interventions that could enhance patient outcomes.
