Analytical Data
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基因名
Sialidase-2
- Application
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别名
Cytosolic sialidase (N-acetyl-alpha-neuraminidase 2)
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种属
Cricetulus griseus
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q64393
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表达区间
1-379aa
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分子量
44.0
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Sialidase-2, also known as neuraminidase 2, is an enzyme that plays a crucial role in sialic acid metabolism, which is essential for various biological processes, including cell signaling, immune response, and pathogen-host interactions. The significance of sialidase-2 has gained attention due to its involvement in several pathological conditions, including cancer progression, inflammation, and viral infections. Recent studies have indicated that aberrant regulation of sialidase-2 can lead to altered glycosylation patterns on cell surfaces, affecting cellular communication and immune evasion mechanisms. Researchers are increasingly focused on understanding the enzyme's structure, functionality, and regulatory mechanisms to elucidate its biological roles. Furthermore, the development of recombinant sialidase-2 presents promising avenues for therapeutic interventions. It could be leveraged in drug discovery, vaccine development, and as a potential biomarker for various diseases. This research is not only pivotal for expanding our knowledge of glycoprotein dynamics but also holds potential for clinical applications in targeting diseases linked to sialic acid dysregulation. Consequently, the exploration of recombinant sialidase-2 is at the forefront of molecular biology and biochemistry research, offering insights that could lead to innovative strategies for disease management and treatment.












