Recombinant Others PET hydrolase Protein，Strep & His

Polyethylene terephthalate (PET) is a widely used synthetic polymer that poses significant environmental challenges due to its durability and resistance to degradation. The accumulation of PET waste has prompted extensive research into effective biodegradation methods, particularly through the use of enzymes that can break down polyester materials. Among these enzymes, PET hydrolases have garnered considerable attention for their ability to catalyze the hydrolysis of PET into its constituent monomers, such as terephthalic acid and ethylene glycol. The identification and characterization of PET hydrolases from various microorganisms, such as the bacterium *Ideonella sakaiensis*, represent a promising avenue for developing biotechnological solutions to plastic waste management. Recent advances in recombinant protein technology have enabled the production of engineered PET hydrolases with enhanced activity and stability, paving the way for their application in industrial settings. Research in this field aims to optimize these enzymes for more efficient PET recycling processes, contributing to a circular economy and reducing the ecological footprint of plastic materials. Additionally, understanding the mechanisms of PET degradation at the molecular level could lead to the discovery of novel enzymes with improved properties, further enhancing the bioremediation potential of these biological catalysts.