Cat: IPD-X24514

Recombinant Human EGR1/ZNF225 Protein,B2M & His

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Analytical Data

  • 基因名

    EGR1/ZNF225

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    AT225 (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24) (KROX24) (ZNF225)

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His-B2M

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P18146

  • 表达区间

    444-543aa

  • 分子量

    24.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

EGR1 (Early Growth Response 1) and ZNF225 (Zinc Finger Protein 225) are both transcription factors implicated in various biological processes, including cell growth, differentiation, and responses to stress. EGR1 is known for its role in immediate early gene expression, acting as a crucial regulator in neuronal development and synaptic plasticity. Its dysregulation has been linked to a variety of conditions, including cancer and neurodegenerative diseases. ZNF225, on the other hand, functions primarily in the regulation of gene expression through its zinc finger motifs, which facilitate the binding to DNA. The study of recombinant proteins of EGR1 and ZNF225 aims to explore their functional roles, molecular interactions, and regulatory mechanisms in cellular pathways. By expressing and purifying these proteins, researchers can conduct various biochemical assays to investigate their potential as targets for therapeutic interventions or as biomarkers for disease states. The recombinant approach also allows for the assessment of post-translational modifications and protein stability, which are critical for their functional activity. Understanding the interplay between EGR1 and ZNF225 may provide insights into their cooperative roles in transcriptional regulation and their implications in health and disease. This research holds promise for developing innovative strategies for managing diseases associated with their aberrant expression.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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