Analytical Data
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Gene name
PRRG2
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简介
PRRG2 protein interacts with NEDD4, suggesting a role in cellular regulation. In addition, it associates with the transcriptional coactivator YAP1, suggesting a possible involvement in transcriptional regulation. PRRG2 Protein, Human (HEK293, Fc) is the recombinant human-derived PRRG2 protein, expressed by HEK293 , with C-mFc labeled tag.
- Application
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Alternative Names
Transmembrane gamma-carboxyglutamic acid protein 2; Proline-rich Gla protein 2; PRGP2; TMG2
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Species
Human
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Source
HEK293
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Tag
C-mFc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14669
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Expression Region
E29-S109
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Protein Length
Partial
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Molecular Weight
37 kDa.
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRRG2 (Proline-Rich Gla-Containing Protein 2) is a member of the PRRG family, which has garnered attention due to its potential roles in various biological processes, including cell differentiation, tissue repair, and response to stress. The protein is characterized by its proline-rich regions and vitamin K-dependent carboxyglutamic acid residues, suggesting important functions in extracellular matrix organization and cell adhesion. Studies have indicated that PRRG2 might play a critical role in the development and progression of certain diseases, including cancers and cardiovascular disorders, as its expression levels are often altered in pathological conditions. Furthermore, the investigation of PRRG2 as a recombinant protein not only facilitates the study of its molecular mechanisms but also provides avenues for therapeutic interventions. Research involving PRRG2 has the potential to enhance our understanding of its biological functions and establish its significance as a biomarker or therapeutic target in disease management, making it a promising focal point for future scientific inquiries.
