Analytical Data
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基因名
CKMT1A
- Application
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别名
CKMT; CKMT1-A; Mia-CK; U-MtCK; Creatine kinase U-type, mitochondrial; Ubiquitous mitochondrial creatine kinase; Acidic-type mitochondrial creatine kinase
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P30275
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表达区间
Glu43~Ile251
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分子量
28kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CKMT1A, or creatine kinase, mitochondrial 1A, is a crucial enzyme involved in energy metabolism, particularly in the regulation of ATP levels within mitochondria. This enzyme is primarily expressed in the heart and skeletal muscles, where it plays a significant role in maintaining cellular energy homeostasis. Mutations in the CKMT1A gene have been linked to various neuromuscular disorders, revealing its critical importance in muscle function and overall energy balance. The study of CKMT1A recombinant protein allows researchers to better understand its structural and functional properties, as well as its role in pathophysiological conditions. By elucidating the enzymatic mechanisms and interactions of CKMT1A, researchers aim to uncover potential therapeutic targets for diseases associated with energy deficiency, such as mitochondrial myopathies. Furthermore, the recombinant form of CKMT1A can be utilized in various biochemical assays, aiding in the development of drugs that can modulate its activity. Overall, research on CKMT1A not only enhances our understanding of mitochondrial function but also holds promise for advancing treatment strategies for energy-related disorders.
