Analytical Data
-
基因名
N Cadherin Protein
- Application
-
种属
Human
-
表达系统
HEK293
-
标签
C-8*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
NP_001783
-
表达区间
D160-A724
-
蛋白长度
Partial
-
分子量
75-90 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
N-cadherin is a type of cadherin, a family of proteins crucial for cell-cell adhesion in various tissues, particularly in the nervous system. It plays a significant role in maintaining the structural integrity of tissues, influencing processes such as embryonic development, neural differentiation, and synaptic plasticity. The study of N-cadherin is vital as its dysfunction is associated with a range of diseases, including cancer metastasis and neurodegenerative disorders. Recombinant N-cadherin protein production allows researchers to investigate its biochemical properties, interactions, and functional mechanisms in detail. By expressing N-cadherin in heterologous systems, scientists can produce large quantities of the protein, enabling the exploration of its role in cellular signaling pathways and adhesion processes. Furthermore, these studies can lead to insights into therapeutic strategies targeting N-cadherin-mediated pathways, potentially offering new avenues for treatment in cancer and other related diseases. Overall, the recombinant N-cadherin protein serves as a valuable tool for advancing our understanding of cell adhesion dynamics and developing targeted interventions in human health.
