Analytical Data
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Gene name
SULT1C4
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简介
The SULT1C4 protein is an important member of the sulfotransferase 1 family and plays a crucial role in phase II drug metabolism and binding of endogenous compounds.Its research enhances the understanding of xenobiotic metabolism and has potential applications in pharmacology.SULT1C4 Protein, Human (His) is the recombinant human-derived SULT1C4 protein, expressed by E.coli , with N-6*His labeled tag.
- Application
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Alternative Names
SULT1C4; Sulfotransferase; SULT1C2; hCG_27301;
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Species
Human
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PD90
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Expression Region
M1-K102
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Protein Length
Full Length
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Molecular Weight
14.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SULT1C4, a member of the sulfotransferase family, plays a crucial role in the metabolism of various endogenous compounds and xenobiotics by catalyzing the sulfate conjugation process. This enzymatic action is essential for the detoxification and elimination of many biologically active molecules, including hormones, neurotransmitters, and drugs. Research on SULT1C4 has gained prominence due to its potential implications in pharmacogenomics and drug metabolism, highlighting its influence on individual responses to medication and susceptibility to diseases. Understanding the functional characteristics and regulatory mechanisms of SULT1C4 can provide insights into its physiological significance and its role in various pathophysiological conditions. Moreover, recombinant SULT1C4 proteins can serve as valuable tools for in vitro studies, enabling the exploration of substrate specificity, kinetic properties, and interactions with different compounds. By elucidating the biochemical pathways involving SULT1C4, researchers aim to establish a clearer connection between genetic variations in the SULT1C4 gene and clinical outcomes, ultimately contributing to more personalized therapeutic approaches. Thus, the investigation of recombinant SULT1C4 proteins not only enhances our understanding of sulfotransferase biology but also opens avenues for targeted drug development and optimization of existing therapeutic strategies.
