Analytical Data
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基因名
KCC4
- Application
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别名
KCC4
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种属
Human
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表达系统
HEK293
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y666-1
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表达区间
M1-S1083
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蛋白长度
Full Length of Isoform-1
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCC4, or K+ Cl- co-transporter 4, is a member of the SLC12 family of solute carriers, primarily involved in the regulation of intracellular ion homeostasis and cell volume. Research on KCC4 has gained traction due to its critical role in various physiological processes and pathophysiological conditions. This protein is predominantly expressed in the kidney, brain, and other tissues, where it helps maintain the ionic balance essential for cellular functions. Dysregulation of KCC4 activity has been linked to several medical conditions, including hypertension, neurological disorders, and cancer. Recent studies have focused on the mechanisms governing KCC4 expression, its interaction with other cellular signaling pathways, and its potential as a therapeutic target. The cloning and expression of recombinant KCC4 have enabled detailed investigations into its functional properties, ion transport mechanisms, and regulatory factors. Understanding the structure-function relationship of KCC4 can pave the way for novel interventions aimed at modulating its activity in disease contexts, highlighting the importance of KCC4 research in both basic science and clinical applications.
