Analytical Data
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基因名
PICK1
- Application
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别名
PRKCABP
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种属
Human
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表达系统
E. coli
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标签
Avi
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRD5-1
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表达区间
F2-S415
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PICK1 (Protein Interacting with C Kinase 1) is a PDZ domain-containing protein that plays a crucial role in various cellular processes, including synaptic transmission, receptor trafficking, and signal transduction. Its significance has garnered attention in the context of neurobiology, particularly due to its involvement in glutamate receptor regulation and neuromodulation, which are critical for brain function and plasticity. Abnormal PICK1 expression or function has been implicated in neurological disorders, such as schizophrenia and addiction, indicating its potential as a therapeutic target. Recent research has focused on elucidating the structural and functional properties of PICK1, particularly its interactions with other proteins and its regulatory mechanisms. The recombinant expression of PICK1 allows researchers to investigate its biochemical activities, protein-protein interactions, and role in cellular signaling pathways. By understanding PICK1's molecular dynamics and its implications in pathophysiology, scientists aim to develop novel strategies for treating diseases linked to its dysregulation. Given its multifaceted role in the nervous system, PICK1 stands out as an important protein for both basic research and potential clinical applications.
