Analytical Data
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基因名
CNOT9
- Application
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别名
RCD1; RQCD1
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种属
Human
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表达系统
E. coli
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标签
Strep;His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92600-1
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表达区间
M1-Q299
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蛋白长度
Full Length of Isoform-1
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CNOT9, a member of the CCR4-NOT complex, plays a crucial role in post-transcriptional regulation, including mRNA degradation and translation control. This protein has gained attention in recent years due to its implications in various biological processes and diseases, particularly in cancer and neurological disorders. Research has shown that CNOT9 is involved in the modulation of gene expression patterns, impacting cellular responses to stress and developmental cues. Additionally, its interactions with other proteins and RNA molecules highlight its importance in maintaining cellular homeostasis. Understanding the function and mechanism of CNOT9 can provide insights into novel therapeutic strategies for diseases where this protein is implicated. The recombinant expression of CNOT9 is essential for biochemical studies, allowing researchers to investigate its structure, function, and interactions in detail. By characterizing CNOT9, scientists aim to uncover potential roles in regulating gene expression networks and identify how perturbations in its function could lead to pathological conditions. This research is pivotal for advancing our knowledge of cellular mechanism and developing targeted interventions in CNOT9-related diseases.
