Analytical Data
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基因名
TCF4
- Application
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别名
TCF4
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种属
Human
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表达系统
E. coli
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标签
Strep;His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NQB0-1
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表达区间
D10-T54
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TCF4 (T-cell factor 4) is a critical transcription factor involved in various cellular processes, including development, differentiation, and oncogenesis. It plays a pivotal role in the Wnt signaling pathway, which is crucial for stem cell regulation and tissue homeostasis. The dysregulation of TCF4 has been implicated in several diseases, particularly in certain cancers and neurodevelopmental disorders, such as schizophrenia. Research has increasingly focused on isolating and characterizing recombinant TCF4 proteins to better understand their structure and functional mechanisms. The use of recombinant technology allows for the production of TCF4 in a controlled environment, facilitating the study of its binding interactions with other proteins and DNA, as well as its role in gene regulation. Investigating TCF4 through recombinant protein studies can provide insights into its potential as a therapeutic target, as the modulation of its activity may influence disease progression. Overall, understanding TCF4's role can contribute to broader knowledge in both developmental biology and disease pathology, driving efforts to develop targeted treatments and interventions.












