Analytical Data
-
Gene name
Collagen XV alpha 1/COL15A1
-
简介
Collagen XV alpha 1 (COL15A1) is a structural protein crucial for stabilizing microvessels and muscle cells, playing a key role in cardiac and skeletal muscle tissues. Its structural support contributes to microvascular and muscle integrity. Additionally, COL15A1 exhibits a potent anti-angiogenic effect, inhibiting angiogenesis and suggesting its role in regulating blood vessel formation. Collagen XV alpha 1/COL15A1 Protein, Human (His) is the recombinant human-derived Collagen XV alpha 1/COL15A1, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of Collagen XV alpha 1/COL15A1 Protein, Human (His) is 189 a.a..
- Application
-
Alternative Names
Collagen alpha-1(XV) chain; COL15A1; Collagen Type XV Alpha 1 Chain
-
Species
Human
-
Source
E. coli
-
Tag
N-10*His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P39059
-
Expression Region
H40-P228
-
Protein Length
Partial
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Collagen XV alpha 1, also known as COL15A1, is a unique member of the collagen family that plays a critical role in the structural integrity and functionality of various tissues, particularly in the extracellular matrix. It is predominantly expressed in connective tissues, such as muscle, skin, and cartilage, and is known for its involvement in cell adhesion, migration, and tissue organization. Recent studies have illustrated that COL15A1 is not only important for normal tissue development but also implicated in various pathological conditions, including fibrosis, cancer progression, and wound healing. Given its significant role, there is an increasing interest in understanding the molecular mechanisms governing COL15A1 expression and function. Recombinant COL15A1 protein has been developed to facilitate detailed research on its biological properties, potential therapeutic uses, and its interactions with other extracellular matrix components. By utilizing recombinant technology, researchers aim to produce high-quality COL15A1 for a variety of applications, including in vitro studies, tissue engineering, and the development of targeted therapies that could mitigate disease processes related to abnormal COL15A1 function. Understanding the implications of COL15A1 in health and disease may lead to innovative approaches in regenerative medicine and novel treatment strategies for collagen-related disorders.
