Analytical Data
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Gene name
ASIP/Agouti
- Application
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Alternative Names
ASP;Agouti switch protein
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P42127
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Expression Region
23-132aa
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Molecular Weight
19.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The ASIP (Agouti Signaling Protein) is a critical regulator of pigmentation in various organisms, primarily studied in mammals. It plays a significant role in determining fur color by modulating the activity of the melanocortin receptors and influencing the production of eumelanin and pheomelanin in melanocytes. Mutations in the ASIP gene have been linked to diverse color phenotypes, making it an important focus of research in genetics, evolutionary biology, and animal breeding. Additionally, ASIP's involvement in metabolic regulation and its potential implications in obesity and metabolic disorders have garnered attention in biomedical research. The recombinant ASIP protein is utilized in various experimental settings to investigate its biological functions, interactions, and signaling pathways. This research not only enhances our understanding of pigmentation genetics but also offers insights into broader physiological processes and potential therapeutic applications. The study of ASIP and its recombinant forms contributes to deciphering the complexities of gene-environment interactions in pigmentation variation and offers avenues for exploring targeted approaches in addressing related health issues.
