Analytical Data
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Gene name
WHSC1
- Application
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Alternative Names
WHSC1; WHSC1 protein
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Species
Human
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Source
Baculovirus
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Tag
N-StrepⅡ;N-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q05CW4
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Expression Region
Q2-K568
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Protein Length
Full Length of Mature Protein (with Propeptide)
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WHSC1, or Wolf-Hirschhorn Syndrome Candidate 1, is a protein encoded by the WHSC1 gene, located on chromosome 4p16.3. This gene is of significant interest in genetic research due to its association with Wolf-Hirschhorn Syndrome (WHS), a rare genetic disorder characterized by developmental delays, growth deficiencies, and a range of physical anomalies. WHSC1 is believed to play a crucial role in key biological processes, including chromatin remodeling and gene regulation, which are vital for normal cellular function and development. Recent studies have shown that WHSC1 is implicated in various cellular pathways involving histone methylation, suggesting its potential involvement in cancer progression and other diseases. Furthermore, research has indicated that alterations in WHSC1 expression can contribute to tumorigenesis, making it a potential target for therapeutic intervention. Despite its significance, understanding WHSC1's precise functions and interactions within the cellular context remains a challenge. The recombinant form of WHSC1 is essential for conducting in-depth studies on its structural properties and biochemical activities, facilitating insights into its role in disease mechanisms and paving the way for the development of targeted therapies. Given the increasing recognition of WHSC1 in health and disease, ongoing research efforts aim to elucidate its functions further, contributing to the broader understanding of genetic disorders and malignancies associated with its dysregulation.
