Cat: IPD-X28265

Recombinant Human WHSC1 Protein (Baculovirus),Strep & His

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Analytical Data

  • 基因名

    WHSC1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    WHSC1; WHSC1 protein

  • 种属

    Human

  • 表达系统

    Baculovirus

  • 标签

    N-StrepⅡ;N-8*His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q05CW4

  • 表达区间

    Q2-K568

  • 蛋白长度

    Full Length of Mature Protein (with Propeptide)

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

WHSC1, or Wolf-Hirschhorn Syndrome Candidate 1, is a protein encoded by the WHSC1 gene, located on chromosome 4p16.3. This gene is of significant interest in genetic research due to its association with Wolf-Hirschhorn Syndrome (WHS), a rare genetic disorder characterized by developmental delays, growth deficiencies, and a range of physical anomalies. WHSC1 is believed to play a crucial role in key biological processes, including chromatin remodeling and gene regulation, which are vital for normal cellular function and development. Recent studies have shown that WHSC1 is implicated in various cellular pathways involving histone methylation, suggesting its potential involvement in cancer progression and other diseases. Furthermore, research has indicated that alterations in WHSC1 expression can contribute to tumorigenesis, making it a potential target for therapeutic intervention. Despite its significance, understanding WHSC1's precise functions and interactions within the cellular context remains a challenge. The recombinant form of WHSC1 is essential for conducting in-depth studies on its structural properties and biochemical activities, facilitating insights into its role in disease mechanisms and paving the way for the development of targeted therapies. Given the increasing recognition of WHSC1 in health and disease, ongoing research efforts aim to elucidate its functions further, contributing to the broader understanding of genetic disorders and malignancies associated with its dysregulation.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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