Analytical Data
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Gene name
CIAO1
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简介
CIAO1 protein is a key player in the cytosolic iron-sulfur protein assembly (CIA) complex, interacting with CIAO2A or CIAO2B and MMS19 to affect different iron-sulfur protein assembly pathways. The CIAO1:CIAO2B:MMS19 assembly facilitates most cytoplasmic and nuclear Fe/S proteins, while the CIAO1:CIAO2A complex contributes to ACO1 maturation and IREB2 stabilization. CIAO1 Protein, Human is the recombinant human-derived CIAO1 protein, expressed by E. coli , with tag free.
- Application
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Alternative Names
CIAO1; Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O76071
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Expression Region
M1-L339
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CIAO1 (Chloroplast Import Associated 1) is a protein that plays a crucial role in the import of proteins into chloroplasts, the organelles responsible for photosynthesis in plant cells. Research on CIAO1 has gained significant attention due to its involvement in the protein translocation pathway, which is essential for chloroplast biogenesis and functionality. Disruption of this pathway can lead to impaired photosynthesis and plant growth, making CIAO1 a valuable target for understanding chloroplast development and its regulation. Studies have identified that CIAO1 interacts with various precursor proteins, facilitating their recognition and import into chloroplasts. Moreover, the characterization of CIAO1 can provide insights into the evolutionary adaptations of plants to environmental stress, as chloroplasts are vital for energy production and metabolic processes. Additionally, investigations into CIAO1 may have broader implications for agricultural biotechnology, as enhancing chloroplast function could improve crop yield and stress resistance. Therefore, the study of CIAO1 not only enriches our understanding of plant biology but also paves the way for potential applications in sustainable agriculture.
