Analytical Data
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Gene name
SLC15A2
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简介
The SLC15A2 protein is a proton-coupled amino acid transporter that prefers dipeptides and transports oligopeptides containing 2 to 4 amino acids. The stoichiometric ratio of protons to peptides is 2:1 or 3:1, which helps the kidneys absorb dipeptides and tripeptides. SLC15A2 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC15A2 protein, expressed by sf9 insect cells , with no tag.
- Application
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Alternative Names
SLC15A2; Solute carrier family 15 member 2; Kidney H(+)/peptide cotransporter; Oligopeptide transporter; kidney isoform; Peptide transporter 2
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Species
Human
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Source
HEK293
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16348
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Expression Region
N2-L729
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Protein Length
Partial
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Molecular Weight
82.5 kDa, based on SDS-PAGE under reducing conditions
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC15A2, a member of the solute carrier family, is primarily involved in the transport of peptide-like molecules across cellular membranes. This transporter is critical for nutrient absorption, particularly in the intestinal and renal systems, where it facilitates the uptake of dipeptides and tripeptides derived from dietary proteins. Recent studies have highlighted its role in the modulation of immune responses and its potential significance in various pathophysiological conditions, including metabolic disorders and cancer. Recombination techniques have allowed researchers to produce SLC15A2 recombinant proteins for functional assays, providing insights into its transport mechanisms and substrate specificity. Understanding the structure-functional relationships of SLC15A2 through these recombinant proteins can pave the way for therapeutic interventions targeting nutrient absorption disorders and enhancing drug delivery systems. Furthermore, elucidating its interaction with other cellular pathways may reveal novel strategies for combating diseases related to impaired transportation of essential biomolecules. Given the growing interest in the role of transporters in pharmacokinetics and drug design, the study of SLC15A2 through recombinant protein expression is increasingly pertinent in the field of biomedicine.
